NCT06635538

One-shot Ovarian Stimulation Protocol (One-shot)

One-Shot Ovarian Stimulation Protocol: A Pilot Study Investigating the Endocrine Profile

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Fundación Santiago Dexeus Font · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

The current prospective observational pilot study aims to evaluate the endocrine profile of a single-injection protocol (single CFA + daily oral administration of CC).

Conditions

• Infertility, Female

Interventions

Type	Name	Description
DRUG	Corifollitropin alfa (CFA) 150 mcg + Clomiphene Citrate (CC) 100 mg/day from D1	On day 2 or 3 of the menstrual cycle or after 5 days of pill-free interval, a single injection of 150 mcg of CFA (Stimulation Day 1) will be administered.
DRUG	Clomiphene Citrate (CC) 100 mg/day from D1	On day 2 or 3 of the menstrual cycle or after 5 days of pill-free interval, the patients will start oral administration of Clomiphene Citrate 100/day continuing up to and including the day of ovulation triggering
DIAGNOSTIC_TEST	Monitoring cycle	Scan controls and blood exams will be performed on stimulation days 1, 6, 8, 10 and, according to clinical needs, until trigger day.

Timeline

• Start date: 2024-10-31
• Primary completion: 2025-04-01
• Completion: 2025-04-01
• First posted: 2024-10-10
• Last updated: 2025-02-26

Locations

3 sites across 1 country: Spain