NCT06631404

Renal Arterial Resistive Index as a Noninvasive Biomarker of Disease Activity in Lupus Nephritis Patients

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 55 (estimated)
• Sponsor: Sohag University · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: —

Summary

Systemic Lupus Erthymatosous (SLE) is achronic inflammatory multi system auto immue disease characterized by pathogenic auto anti bodies production against nuclear structures (Bolouri et al.,2022), SLE affecting mainly woemn of childbearing age and is chracterized by unpredictable flares and remissions , disease variety varied from mild episode disorder to arpidly progressive life -threatening illness.. LN is diagnosed by either the presence of proteinuria \>0.5g/day. active urinary sediment , or an unexplained rise in serum creatinine there fore , identifying new invasive biomarkers of LN severity and outcome is mandatory, Renal Arterial resistive index ( RRI) is anon invasive biomarker that has been studied as apotential indicator of disease activity in LN patients.

Conditions

• Lupus Nephritis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	renal doppler	doppler srudy on renal arteries bilaterally , and detection of RI of renal artery

Timeline

• Start date: 2024-10-01
• Primary completion: 2025-10-30
• Completion: 2025-10-30
• First posted: 2024-10-08
• Last updated: 2024-10-08

Locations

1 site across 1 country: Egypt