NCT06624683

Exploring the Effect of Footbaths on Increasing the Success Rates in Vitro Fertilization

Exploring the Effect of Footbaths on Increasing the Success Rates of in Vitro Fertilization and Its Associated Mechanism

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: National Taipei University of Nursing and Health Sciences · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

To evaluate the effectiveness of warm-water footbaths in enhancing pregnancy rates during IVF and to explore the underlying mechanisms involved.

Detailed description

Additionally, this research will assess whether a complementary and alternative medicine (CAM) approach utilizing warm-water footbaths is effective in improving pregnancy rates for women undergoing IVF. Furthermore, the potential mechanisms by which footbaths may enhance IVF success rates will be elucidated. The specific aims of this research proposal are as follows: 1. To explore the correlation between health statuses, sleep quality, stress, and infertility incidence. 2. To investigate the association between health statuses, sleep quality, stress, and multiple inflammatory indexes in infertile women, including: 2-1. Systemic immune inflammation index (SII) 2-2. Lymphocyte count (LC) 2-3. Platelet and neutrophil count product (PPN) 2-4. Platelet-lymphocyte ratio (PLR) 2-5. Neutrophil-lymphocyte ratio (NLR) 2-6. Lymphocyte-monocyte ratio (LMR) 3. The effects of Footbaths on Stress and Sleep: To examine the effects of footbaths on reducing stress and improving sleep quality, which may enhance pregnancy success rates during IVF treatment in infertile women. 4. The impact on Inflammatory Markers: To investigate whether footbaths can reduce levels of inflammatory markers and inflammatory cytokines during IVF treatment, potentially enhancing pregnancy success rates in infertile women.

Conditions

• Infertility
• In Vitro Fertilization

Interventions

Type	Name	Description
DEVICE	Intelligent footbath basin	before night sleep, takes 30 mins, starting from the first day of the menstrual cycle (MC) and continuing for 28 days.

Timeline

• Start date: 2024-10-01
• Primary completion: 2025-07-01
• Completion: 2025-10-01
• First posted: 2024-10-03
• Last updated: 2024-10-03

Locations

1 site across 1 country: Taiwan