NCT06623500

Iodine Nutrition Status and Clinical Characteristics of Thyroid Cancer

Prospective Cohort Study on Clinical Characteristics of Thyroid Cancer in Different Iodine Status Areas

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,600 (estimated)
• Sponsor: Shandong Provincial Hospital · Other Government
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The effect of iodine nutritional status on thyroid cancer has been controversial for many years. We designed a prospective cohort study that recruiting patients in different iodine areas who underwent thyroid cancer surgery in branch hospitals from 2012 to 2019，and follow up their clinical outcomes. We aimed to analyse the relationship between regional iodine nutrition level and pathological types, clinical features, and prognosis of thyroid cancer.

Detailed description

Three sub centers were selected in high iodine (Jining/Liaocheng/Heze) and moderate iodine (Jinan/Shenyang/Haerbin) areas respectively. Patients lived in the above-mentioned regions for at least 5 years and diagnosed as thyroid cancer and underwent thyroid surgery in branch hospitals from 2012 to 2019 were recruited.

Conditions

• Thyroid Cancer

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Iodine excess	Iodine excess areas: water iodine ≥100μg/L; or urinary iodine concentration (median urinary iodine levels in children aged 8-10 years old)≥300μg/L
DIETARY_SUPPLEMENT	Iodine suitable	Iodine suitable areas：water iodine ≥40μg/L and ≤100μg/L; or urinary iodine concentration(median urinary iodine levels in children aged 8-10 years old) 100-199μg/L.

Timeline

• Start date: 2012-01-01
• Primary completion: 2026-12-01
• Completion: 2026-12-31
• First posted: 2024-10-02
• Last updated: 2024-10-02

Locations

1 site across 1 country: China