Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06623487

The Application Value of 68Ga-grazytracer PET in Immunotherapy for Stage III Non-small-cell Lung Cancer

The Application Value of 68Ga-grazytracer PET in Immunotherapy for Stage III Non-small-cell Lung Cancer: a Prospective, Observationa Trial

Status
Recruiting
Phase
Study type
Observational
Enrollment
30 (estimated)
Sponsor
Ruijin Hospital · Academic / Other
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

Neoadjuvant immunotherapy can significantly improve the pathological complete response (pCR) and major pathological response (MPR) rates in resectable stage III non-small cell lung cancer (NSCLC), and extend the event-free survival (EFS). However, the current means for evaluating its efficacy are limited. This study aims to utilize the convenient and non-invasive 68Ga-grazytracer PET imaging to detect the aggregation of CD8+ T cells in target lesions after neoadjuvant immunotherapy for stage III NSCLC, and to assess its value in efficacy monitoring, providing valuable information for clinical treatment decisions.

Conditions

Timeline

Start date
2024-07-19
Primary completion
2026-06-30
Completion
2027-07-31
First posted
2024-10-02
Last updated
2024-10-02

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT06623487. Inclusion in this directory is not an endorsement.