NCT06619665

A Study of MK-6552 in Sleep Deprived Healthy Participants (MK-6552-003)

A Randomized, Double-blind, 3-Period Crossover Study to Assess the Effects of MK-6552 on Sleep Latency in Sleep Deprived Healthy Participants With Modafinil as a Positive Control

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 18 (actual)
• Sponsor: Merck Sharp & Dohme LLC · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

This study examined the safety of the drug MK-6552 and if people tolerated it. It also studied whether MK-6552 works better than placebo for staying awake in sleep deprived healthy participants.

Conditions

• Healthy
• Narcolepsy

Interventions

Type	Name	Description
DRUG	MK-6552	MK-6552 gelatin coated capsules taken orally two times 8 hours apart
DRUG	MK-6552 placebo	MK-6552 placebo gelatin coated capsules taken orally two times 8 hours apart
DRUG	Modafinil	Modafinil tablet taken once orally
DRUG	Modafinil placebo	Modafinil placebo tablet taken once orally

Timeline

• Start date: 2024-03-19
• Primary completion: 2024-07-16
• Completion: 2024-07-16
• First posted: 2024-10-01
• Last updated: 2024-10-01

Locations

2 sites across 1 country: United States

Regulatory

• FDA-regulated drug study