NCT06617910

Stereotactic Radiotherapy for Sinonasal Malignancy

Treatment Outcomes and Dosimetric Analysis Comparison Between CyberKnife and VMAT Based Methods of Stereotactic Radiotherapy for Sinonasal Malignancy

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 16 (actual)
• Sponsor: Taichung Veterans General Hospital · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

Sinonasal Tumors are a rare type of head and neck tumor, accounting for approximately 3% of head and neck cancers. Treatment primarily involves surgical intervention, with radiation therapy as an adjunct. Due to the tumor\'s anatomical location near critical structures such as the eyes, optic nerves, optic chiasm, brainstem, and oral cavity, if the tumor cannot be completely resected, postoperative radiation therapy is often necessary. Given the complexity of the tumor\'s anatomical position, subsequent radiation therapy planning becomes more challenging, as it must balance tumor control and organ preservation. This study retrospectively analyzes patients with sinonasal tumors who received stereotactic radiosurgery (CyberKnife) at our hospital, comparing the dosimetric advantages, treatment efficacy, survival analysis, and side effects with those of volumetric modulated arc therapy (VMAT).

Conditions

• Head and Neck Neoplasms

Interventions

Type	Name	Description
RADIATION	SBRT by Cyberknife	The patients with sinonasal maliganacy receive curative surgery then receive adjuvant RT by the method of SBRT by Cyberknife.

Timeline

• Start date: 2023-09-01
• Primary completion: 2024-08-31
• Completion: 2025-08-31
• First posted: 2024-10-01
• Last updated: 2024-10-01

Locations

1 site across 1 country: Taiwan