NCT06617039

The Impact of Low-Dose Esketamine Combined With Ciprofol on the Quality of Early Postoperative Recovery Among Elderly Patients Undergoing Painless Gastroscopy

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 376 (estimated)
• Sponsor: Northern Jiangsu People's Hospital · Academic / Other
• Sex: All
• Age: 60 Years – 75 Years
• Healthy volunteers: Accepted

Summary

To explore the impact of esketamine combined with ciprofol on the quality of early postoperative recovery in elderly patients undergoing painless gastroscopy, as well as the effectiveness and safety of this regimen.

Conditions

• Quality of Postoperative Recovery

Interventions

Type	Name	Description
DRUG	Remifentanil and ciprofol	R group will be started with remifentanil 0.5ug/kg and ciprofol 0.4 mg/kg.
DRUG	esketamine 0.3mg/kg and ciprofol	Anesthesia induction was initiated by esketamine 0.3mg/kg, followed by ciprofol 0.2-0.4mg/kg.
DRUG	esketamine 0.5mg/kg and ciprofol	Anesthesia induction was initiated by esketamine 0.5mg/kg, followed by ciprofol 0.2-0.4mg/kg.
DRUG	Ciprofol	Ciprofol group will be started with ciprofol 0.2-0.4 mg/kg.

Timeline

• Start date: 2024-10-10
• Primary completion: 2025-07-15
• Completion: 2025-07-15
• First posted: 2024-09-27
• Last updated: 2025-05-07

Locations

1 site across 1 country: China