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Active Not RecruitingNCT06616168

Urogenital Infections in Women of Reproductive Age and the Activity of 4-Thiazolidinone Derivatives Against Pathogens

Ministry of Health of Ukraine No. 2264 from 15.12.2022, Ministry of Health of Ukraine No. 310 from 08.05.2014, Ministry of Health of Ukraine No. 928 from 18.05.2023

Status
Active Not Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
200 (estimated)
Sponsor
Danylo Halytsky Lviv National Medical University · Academic / Other
Sex
Female
Age
15 Years – 49 Years
Healthy volunteers
Not accepted

Summary

Research concerning women pathogenic microflora during different conditions

Detailed description

Study of microflora of different groups of women of reproductive age, determination of pathogens and their further study, samples of a newly synthesized compound on isolated pathogens

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTMicrobiological identification kits (ANAEROtest, STAPHYtest, ENTEROtest, NEFERMtest)Microbiological identification kits (ANAEROtest, STAPHYtest, ENTEROtest, NEFERMtest) produced by Erba Lachema leads to bacteria detection via biochemical features
DRUGAntibiotic therapy after the results of antibiotic sensitivity test (Mostly Oxacillin, Benzylpenicillin, Ceftriaxone, Doxycycline, Clindamycin)Antibiotic therapy after the results of antibiotic sensitivity test. Aminoglycosides, Carbapenems, Cephalosporins, Fluoroquinolones, Oxazolidinones are used. Mostly Oxacillin, Benzylpenicillin, Ceftriaxone, Doxycycline, Clindamycin are used for the therapy.
COMBINATION_PRODUCTSuppositoria for vaginal microflora recovery (Giynoflor)Prescription of suppositoria for vaginal microflora recovery after antibiotic therapy. Probiotic grug includes Lactobacilli acidophillis as the main compound.
DRUGAntifungal therapy (Mostly Fluconazole, Nystatin, Amphotericin B)Prescription of antifungal drugs. Triazoles (Fluconazole, Itraconazole, Voriconazole), Imidazoles (Ketoconazole), Nystatin and Amphotericin B are used the most

Timeline

Start date
2023-09-01
Primary completion
2026-08-31
Completion
2027-08-31
First posted
2024-09-27
Last updated
2024-09-27

Locations

1 site across 1 country: Ukraine

Source: ClinicalTrials.gov record NCT06616168. Inclusion in this directory is not an endorsement.