NCT06614348

Prednisolone Acetate Eye Drops for Pain Intervention in Second Eye Cataract Surgery

A Randomized Controlled Study of Prednisolone Acetate Eye Drops for Pain Intervention in Second Eye Cataract Surgery

• Status: Not Yet Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine · Academic / Other
• Sex: All
• Age: 50 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate the efficacy, safety, and potential mechanisms of prednisolone acetate eye drops for pain management in patients undergoing second-eye surgery for age-related cataracts. Researchers will compare prednisolone acetate eye drops to sodium hyaluronate eye drops to see if prednisolone acetate eye drops work to relieve intraoperative and postoperative pain during second-eye cataract surgery. Participants will: 1. Receive prednisolone acetate eye drops or sodium hyaluronate eye drop four drops within 2 hours before cataract surgery 2. Finish cataract surgery and routine postoperative follow-up 3. Pain questionnaire completed after cataract surgery

Conditions

• Age Related Cataract
• Pain Management During Cataract Surgery

Interventions

Type	Name	Description
DRUG	Prednisolone acetate eye drop group	Patients receive prednisolone acetate eye drops 4 times per 30min within 2 hours before cataract surgery
DRUG	Sodium hyaluronate eye drops	Patients receive sodium hyaluronate eye drops 4 times per 30min within 2 hours before cataract surgery

Timeline

• Start date: 2024-10-08
• Primary completion: 2025-06-30
• Completion: 2025-11-30
• First posted: 2024-09-26
• Last updated: 2024-09-26