NCT06611683

Effect of Inspiratory Muscle Training on Ventilated Patients in an Intensive Care Unit

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Chang Gung University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to learn if inspiratory muscle training facilite the liberation of mechanical ventilation. The main questions it aims to answer are: Does inspiratory muscle training facilitate weaning from mechanical ventilation and enhance muscle strength in critically ill, subacute adult patients? The main questions it aims to answer are: Does pulmonary rehabilitation facilitate wwaning form mechanical patients? Does the intervention improve respiratory muscle strength and respiratory patterns? Participants received: Inspriatory muscle training twice daily for three consecutive weeks or until the subject no longer required ventilator support.

Detailed description

Patients on mechanical ventilation often experience rapid diaphragm atrophy on the second day, resulting in muscle fiber changes, respiratory muscle weakness. Clinical studies have explored enhancing diaphragm and respiratory muscle strength and endurance through inspiratory muscle, expiratory muscle, and combined respiratory muscle training. This study was to determine if inspiratory muscle training significantly facilitates liberation from mechanical ventilation and improves muscle strength when compared to without IMT among subacute critically ill adult patients.

Conditions

• Critically Ill, Subacute Adult Patients
• Mechanically Ventilation

Interventions

Type	Name	Description
PROCEDURE	Inspiratory muscle training	A threshold inspiratory muscule device used a starting resistance set at 30% maximum inspiratory pressure, connecting to subject artificial airway. The subjects were then instructed to perform fast and forceful inspirations against added inspiratory resistance. The inspiratory muscle training was conducted twice daily over five consecutive days, followed by a two-day rest period. This regimen continued for three consecutive weeks or until the subject no longer required ventilator support.
PROCEDURE	Routine care	Subjects received routine care without intervention.

Timeline

• Start date: 2019-07-01
• Primary completion: 2020-12-31
• Completion: 2020-12-31
• First posted: 2024-09-25
• Last updated: 2024-10-03

Locations

1 site across 1 country: Taiwan