NCT06609967

Effect Of Autologous Platelet Rich Fibrin On Post-Operative Complications And Healing Following The Extraction

Effect Of Autologous Platelet Rich Fibrin (PRF) On Post-Operative Complications And Healing Following The Extractions Impacted Mandibular Wisdoms

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Dow University of Health Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

As post-operative pain, infection inflammation and infections are the main complications after the surgical extraction of the lower third molar the aim of this study is to compare the healing effects of PRF administered postoperatively

Detailed description

PRF will be randomly administered into one group of patients undergoing any extractions group A (Right after the extraction) Group B will be a control group in which extraction sockets will be left to heal with the natural blood clot. Consenting patients will be assigned into groups randomly and not informed which group they were placed into. The PRF will be administered obtained from a tube of 10 ml blood and no material will be placed in the control group. The progress of healing and post-operative complications will be tracked over a period of 7 days with patients being called for follow-up on days 3, 5 and 7. Their post-operative complications will be checked at every subsequent visit and noted in the questionnaire. The Questionnaire is structured and will be interviewer-administered. It will comprise of basic bio-demographic data (such as name, age, sex, etc) and 3 closed-ended questions related to post-operative complications following the extraction

Conditions

• Pain, Postoperative
• Post Operative Swelling
• Trismus
• Soft Tissue Healing

Interventions

Type	Name	Description
PROCEDURE	application of PRF	PRF will be randomly administered into one group of patients undergoing any extractions group A (Right after the extraction) Group B will be a control group in which extraction sockets will be left to heal with the natural blood clot. Consenting patients will be assigned into groups randomly and not informed which group they were placed into. The PRF will be administered obtained from a tube of 10 ml blood and no material will be placed in the control group. The progress of healing and post-operative complications will be tracked over a period of 7 days with patients being called for follow-up on days 3, 5 and 7
PROCEDURE	application of conventional surgicel	it will be a control group in which extraction sockets will be left to heal with the natural blood clot.

Timeline

• Start date: 2021-11-15
• Primary completion: 2022-06-01
• Completion: 2022-08-30
• First posted: 2024-09-24
• Last updated: 2024-09-24

Locations

1 site across 1 country: Pakistan