NCT06609746

Effectiveness of Thyme in the Management of Clinical Symptoms in Patients with Irritable Bowel Syndrome

The Effect of Low FODMAP (Fermentable, Oligo-, Di-, Mono-saccharides and Polyols) Diet with Thyme on Clinical Symptoms and Quality of Life in Patients with Irritable Bowel Syndrome

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 52 (estimated)
• Sponsor: Shahid Beheshti University of Medical Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to learn if thyme supplement enhances the effects of a low FODAMP diet on reducing clinical symptoms and improving the quality of life of patients with irritable bowel syndrome or not. The main questions it aims to answer are: 1. Does consumption of thyme reduce the severity score of clinical symptoms in patients with irritable bowel syndrome? 2. Does consumption of thyme increase the quality of life score in patients with irritable bowel syndrome? Researchers will compare thyme supplementation with placebo to see if thyme supplement enhances the effects of a low FODAMP diet on clinical symptoms and quality of life in patients with irritable bowel syndrome. Participants will: 1. Receive thyme supplement plus a low FODMAP diet or placebo with low FODMAP diet for 8 weeks. 2. Recorde 3 days (1weekend and 2 workday) dietary recalls at week 4 and week 8 to assess adherence to the low FODMP diet. 3. Visit the clinic at the beginning of the study and the end of the study for a check-up and score record

Conditions

• Irritable Bowel Syndrome (IBS)

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Thyme extract	Three Gastrolit capsules daily with a low FODMAP diet for 8 weeks
OTHER	Placebo	Placebo capsules daily with a low FODMAP diet for 8 weeks

Timeline

• Start date: 2024-10-21
• Primary completion: 2025-03-01
• Completion: 2025-04-01
• First posted: 2024-09-24
• Last updated: 2024-09-24