NCT06609382

Left Ventricular Mass Index Predicts Clinical Outcomes in Patients with Obstructive Hypertrophic Cardiomyopathy Undergoing Septal Myectomy

Prognostic Value of Left Ventricular Mass Index in Obstructive Hypertrophic Cardiomyopathy Undergoing Septal Myectomy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 490 (actual)
• Sponsor: Changrong Nie · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In this study, we aimed to analyze the association between left ventricular mass index and clinical outcomes to provide the potential indicator for worse survival.

Detailed description

This retrospective study aimed to determine the prognostic value of left ventricular mass index in predicting clinical outcomes, including all-cause death, new-onset or recurrent atrial fibrillation, and a composite endpoint of all-cause death, heart failure,permanent pacemaker implantation, new-onset or recurrent atrial fibrillation, and stroke.

Conditions

• Obstructive Hypertrophic Cardiomyopathy (oHCM)

Interventions

Type	Name	Description
OTHER	Patients had a higher left ventricular mass index or not （the exact value is determined by the cut-off value for the clinical outcomes)	Patients were grouped by the cutoff value of left ventricular mass index (LVMI) for all cause death, and the Maximally Selected Rank Statistics method was used to determine the optimal cutoff point of LVMI for death.

Timeline

• Start date: 2011-06-01
• Primary completion: 2020-12-31
• Completion: 2020-12-31
• First posted: 2024-09-24
• Last updated: 2024-09-24

Locations

1 site across 1 country: China