NCT06608290

Paraesternal Blockade and Lactate Serum Levels in Patients With Cardiac Surgery.

Association Between the Application of Parasternal Blockade and Serum Lactate Level in Trans and Post-anesthetic Stages in Cardiac Surgery.

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 86 (actual)
• Sponsor: Instituto Mexicano del Seguro Social · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Parasternal blockade has been related to a reduction of the postoperative inflammatory response, by inhibition of the stress response, leading to a better prognosis. Increased lactate level is a useful parameter in identifying patients at risk of postoperative morbidity and mortality. The objective was to evaluate the association between parasternal blockade and serum lactate level in patients undergoing cardiac surgery, both trans- and post-anesthesia. 86 patients between 60-70 years of age participated. An association was found between the application of parasternal blockade in cardiac surgery and the presence of lower trans and postanesthetic serum lactate levels.

Detailed description

An analytical cross-sectional study in adult patients who underwent elective cardiac surgery. A total sample of 86 patients was obtained, 43 in the case group and 43 in the control group. Adult patients older than 18 years, of either sex, with ASA II-III, patients who underwent cardiac surgery with median sternotomy and use of cardiopulmonary bypass were included.

Conditions

• Parasternal Block
• Cardiac Surgery
• Serum Lactate

Interventions

Type	Name	Description
PROCEDURE	parasternal block	Administration of parasternal block with ropivacaine, bilaterally at the sternum before the start of surgery.
DIAGNOSTIC_TEST	Lactate serum level	Blood samples were taken to identify serum lactate levels greater than 2 mmol/l and those that remained below this limit.

Timeline

• Start date: 2022-01-01
• Primary completion: 2022-12-31
• Completion: 2024-09-02
• First posted: 2024-09-23
• Last updated: 2024-09-24

Locations

1 site across 1 country: Mexico