NCT06604325

Prophylactic Tranexamic Acid To Reduce Blood Loss During Caesarean Delivery.

Prophylactic Role Of Tranexamic Acid To Reduce Blood Loss During Caesarean Delivery : A Prospective Study.

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Aligarh Muslim University · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

Postpartum hemorrhage continues to be the leading cause of maternal morbidity and mortality. Globally, it is responsible for 25% of all pregnancy-related deaths. PPH is unpredictable and may occur in the absence of risk factors. Tranexamic acid is an antifibrinolytic proven to reduce blood loss and transfusion requirements for various surgeries. This study aims to explore the effectiveness of tranexamic acid as an adjunct to other uterotonics before the Caesarian Section.

Conditions

• Post Partum Hemorrhage

Interventions

Type	Name	Description
DRUG	Tranexamic acid injection	All women recruited to Group A will receive tranexamic acid 1 gram in 100 ml Normal Saline as intravenous infusion 10 minutes before the skin incision.
DRUG	Placebo	All women recruited to Group B will receive 100 ml Normal Saline as intravenous infusion 10 minutes before the skin incision.

Timeline

• Start date: 2024-10-01
• Primary completion: 2025-03-30
• Completion: 2025-03-30
• First posted: 2024-09-19
• Last updated: 2024-10-24

Locations

1 site across 1 country: India