NCT06604273

Unravelling Intestinal Fibrosis in Ulcerative Colitis

• Status: Recruiting
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The main objectives are: (i) to identify candidate fibrotic cellular pathways in UC patients treated with a JAK inhibitor filgotinib), and (ii) to detect and monitor in vivo fibrosis in UC patients using FAPi-PET/CT imaging

Conditions

• Ulcerative Colitis (UC)
• Inflammatory Bowel Disease (IBD)
• Fibroblast Activation Protein Inhibitor

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Fibroblast Activation Protein Inhibitor	PET CT imaging using the fibroblast activation protein inhibitor tracer

Timeline

• Start date: 2024-04-03
• Primary completion: 2025-10-03
• Completion: 2026-04-03
• First posted: 2024-09-19
• Last updated: 2024-09-19

Locations

1 site across 1 country: Netherlands