NCT06601738

Isometric and Dynamic Handgrip Training Effects on Hypertension

Effects Of Isometrics and Dynamic Handgrip Exercise Training On Cardiovascular Parameters In Hypertensive Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Riphah International University · Academic / Other
• Sex: All
• Age: 30 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

Essential hypertension accounts for 13 percent of total deaths worldwide, accounting for one of the major risk factors. Hypertension (high blood pressure) is when the pressure in your blood vessels is too high (140/90 mmHg or higher). Dynamic exercises, sustained hand grip contractions elicit lower systolic blood pressure and heart rate responses. So for patients undergoing exercise therapy, low intensity isometric exercises are preferable. Significant reduction is seen in mean arterial blood pressure and systolic blood pressure in individuals conducting isometric for 8 weeks in 30%. The reduction in systolic blood pressure will be clinically significant. The main objective of this study will be to determine the effects of dynamic and isometric handgrip exercise training on cardiovascular parameters in hypertensive patients Grade 1 hypertensive patients are included as per AHA and JNC7 criteria. A sample of 100 hypertensive patients will be recruited and divided into two treatment groups; G1: dynamic exercise in hypertensive patients, and G2: isometric exercise in hypertensive patients. Outcome measure will include systolic blood pressure, diastolic blood pressure, mean arterial blood pressure and pulse pressure. Outcome measures will be assessed at baseline and 2nd and 4th weeks posttreatment.

Detailed description

Hypertension is one of the most prevalent diseases leading to morbidity and mortality, affecting millions of people every year. Pharmaceutical management is the main treatment method used. Exercise therapy mainly isometrics and dynamic handgrip exercises provide a non pharmacological management leading to decrease in symptoms. The association of hypertension with physical inactivity, sedentary behavior, and occupational exposure to chemicals, obesity, older age, genetics, being overweight or obese, not being physically active, ,high-salt diet, job insecurity, job loss, and the psychosocial work environment and drinking too much alcohol. Lifestyle changes like eating a healthier diet, quitting tobacco, and being more active can help lower blood pressure. Hypertension rates are strongly associated with age. Acute effects of isometric and dynamic handgrip exercise on cardiovascular parameters in hypertensive subjects are numerous . They may also have some adverse effects on the cardiorespiratory system, particularly, through the elevation of blood pressure. Since an acute bout of exercise can transiently improve cardiovascular endothelial function, arterial stiffness, and ambulatory blood pressure. The dynamic handgrip exercise is performed by repetitive contraction and relaxation of the hand at a maximum frequency. In order to determine the intensity of handgrip exercises, maximum isometric handgrip strength of the right and left hand was measured with a handgrip dynamometer. Isometric exercises differ from dynamic exercises because in this there is no change in muscle length or static force. Single handgrip exercise could reduce the blood pressure for couple of hours so a patient can perform this exercise several times a day if not being fatigue.

Conditions

• Hypertension

Interventions

Type	Name	Description
OTHER	Isomeric Hand Grip Exercises	Patients will be instructed to squeeze and sustain the dynamometer for 2 min at 30% M.V.C. The dynamometer pointer which read the scale provided visual feedback to the subjects for the maintenance of the 30% M.V.C. This procedure will be repeated twice for each training session with a 5-minute rest in between.
OTHER	Dynamic Hand Grip Exercises	Dynamic handgrip exercise was performed with both-sided, metronome-guided rhythmic hand contractions for 2min. The handgrip ring, closest to 20% of MVC, was chosen for DHE which was performed at a frequency of 30/min, acoustically indicated by a metronome beat.

Timeline

• Start date: 2024-08-30
• Primary completion: 2024-12-30
• Completion: 2025-01-30
• First posted: 2024-09-19
• Last updated: 2025-06-15

Locations

1 site across 1 country: Pakistan