Trials / Not Yet Recruiting
Not Yet RecruitingNCT06599411
Identification of Cutaneous and Blood Biomarkers Predictive of Response to Systemic Treatments During Chronic Inflammatory Skin Diseases
Identification Des Marqueurs Biologiques cutanés et Sanguins prédictifs de réponse Aux Traitements systémiques au Cours Des Maladies cutanées Inflammatoires Chroniques
- Status
- Not Yet Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 700 (estimated)
- Sponsor
- Assistance Publique - Hôpitaux de Paris · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
Chronic inflammatory skin diseases constitute a heterogeneous group of pathologies. They affect the skin but also other organs (joints, lungs, muscles, etc.). Their prognosis and response to treatments is extremely variable. The discovery of prognosis factors will help to precisely guide the treatment regimen and its intensification based on individual markers. The identification of new therapeutic targets is essential to develop new innovative treatments for inflammatory skin diseases. The main objective is to identify new cellular or molecular prognostic factors associated with treatment response at 1 year in inflammatory skin diseases. The secondary objectives are a better understanding of the pathophysiology of chronic inflammatory skin diseases, the identification of new cellular, molecular and microbiological prognostic factors associated with the clinical state after 10 years of evolution and the identification of prognostic markers of drug toxicity.
Conditions
- Atopic Dermatitis
- Psoriasis
- Hidradenitis Suppurativa
- Lichen Planus
- Cutaneous Lupus
- Dermatomyositis
- Cutaneaous Scleroderma
- Neutrophilic Dermatosis
- Cutaneous Granulomatosis
- Active Leprosy
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Sampling | Collection of an additional volume of blood Superficial skin biopsy Skin swab |
| OTHER | Sampling | Collection of an additional volume of blood Preservation of post-operative skin remnants Skin swab |
Timeline
- Start date
- 2024-10-01
- Primary completion
- 2035-10-01
- Completion
- 2044-10-01
- First posted
- 2024-09-19
- Last updated
- 2024-09-19
Source: ClinicalTrials.gov record NCT06599411. Inclusion in this directory is not an endorsement.