Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06595160

Determining the Link Between Dietary Patterns, Fecal Microbiome and Response to Neoadjuvant Chemotherapy

Determining the Link Between Dietary Patterns, Fecal Microbiome and Response to Neoadjuvant Chemotherapy in Pancreatic Ductal Adenocarcinoma Patients

Status
Recruiting
Phase
Study type
Observational
Enrollment
87 (estimated)
Sponsor
Emory University · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study explores the relationship between pre-treatment dietary patterns, fecal microbiome, and response to chemotherapy in patients with pancreatic ductal adenocarcinoma.

Detailed description

PRIMARY OBJECTIVES: I. Evaluate the association between pre-treatment diversity of the fecal microbiome and major pathological response to neoadjuvant chemotherapy in operable pancreatic ductal adenocarcinoma patients. II. Evaluate the association between pre-treatment HEI-2015 dietary score and major pathological response to neoadjuvant chemotherapy in pancreatic ductal adenocarcinoma patients. III. Evaluate the association between pre-treatment HEI-2015 dietary score and diversity of the fecal microbiome in pancreatic ductal adenocarcinoma patients. OUTLINE: This is an observational study. Patients complete a dietary survey and undergo fecal sample collection on study.

Conditions

Interventions

TypeNameDescription
OTHERNon-Interventional StudyNon-interventional study

Timeline

Start date
2024-08-05
Primary completion
2026-04-30
Completion
2027-08-07
First posted
2024-09-19
Last updated
2025-08-01

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT06595160. Inclusion in this directory is not an endorsement.