Clinical Trials Directory

Trials / Completed

CompletedNCT06593938

A Study to Evaluate the Efficacy and Safety of Oral HRS-5965 in Adult Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Who Are Naive to Complement Inhibitor Therapy

A Multicenter, Randomized, Open-label, Active-comparator Controlled Phase III Study to Evaluate the Efficacy and Safety of HRS-5965 Capsule in Patients With Paroxysmal Nocturnal Hemoglobinuria

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
76 (actual)
Sponsor
Chengdu Suncadia Medicine Co., Ltd. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

A study of the efficacy and safety of HRS-5965 capsules compared to eculizumab for 24 weeks in patients with PNH.

Conditions

Interventions

TypeNameDescription
DRUGHRS-5965 capsuleHRS-5965 capsule for 24 weeks
DRUGEculizumab InjectionEculizumab Injection for 24 weeks

Timeline

Start date
2024-10-25
Primary completion
2025-07-31
Completion
2025-07-31
First posted
2024-09-19
Last updated
2025-09-11

Locations

2 sites across 1 country: China

Source: ClinicalTrials.gov record NCT06593938. Inclusion in this directory is not an endorsement.