NCT06592937

Harmonized and Pooled Database, Named PRIME.

Potentially Modifiable Ventilation Factors Associated With Outcome in Neurocritical Care vs Non-Neurocritical Care Patients - Rational and Protocol for a Patient-Level Analysis of PRoVENT, PRoVENT-iMiC and ENIO (PRIME)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 3,270 (actual)
• Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: —

Summary

We merged the dataset of three large observational studies of invasive ventilation in critically ill patients.

Detailed description

PRIME contains the individual patient data of 3 large observational studies of ventilation, 'PRactice of VENTilation in critically ill patients without ARDS' (PRoVENT), 'PRactice of VENTilation in critically ill patients in Middle-income Countries' (PRoVENT-iMiC) and 'Extubation strategies and in neuro-intensive care unit patients and associations with outcomes' (ENIO).

Conditions

• Invasive Ventilation

Interventions

Type	Name	Description
OTHER	Invasive ventilation	Invasive ventilation and respiratory support

Timeline

• Start date: 2024-01-01
• Primary completion: 2024-07-26
• Completion: 2024-07-26
• First posted: 2024-09-19
• Last updated: 2024-09-19

Locations

1 site across 1 country: Netherlands