NCT06592118

Clinical and Surgical Outcomes of Thyroid Carcinoma in Children and Adolescents

Clinical Profiles, Surgical Strategies, and Outcomes of Follicular and Papillary Thyroid Carcinoma in Pediatric and Adolescent Populations: A Retrospective Comparative Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 3,068 (actual)
• Sponsor: Dezhou Hospital Qilu Hospital of Shandong University · Academic / Other
• Sex: All
• Age: 1 Year – 18 Years
• Healthy volunteers: Not accepted

Summary

This study aims to investigate the differences in clinical characteristics, causes of death, long-term survival, and surgical approaches between pediatric and adolescent follicular and papillary carcinoma by exploring data from the SEER database. The research is designed as a retrospective cohort study, primarily focused on collecting and comparing data to identify key disparities and outcomes between these two patient groups. It is anticipated that the findings will provide valuable insights into the management and prognosis of these cancers in younger populations, contributing to more targeted and effective treatment strategies.

Detailed description

This study is a retrospective cohort analysis aimed at elucidating the differences between pediatric and adolescent patients diagnosed with follicular and \[specific type\] carcinoma, utilizing data sourced from the SEER (Surveillance, Epidemiology, and End Results) database. The focus of the research is on a comprehensive comparison of various clinical aspects, including demographic characteristics, tumor features, treatment modalities, and survival outcomes. Key areas of investigation include the examination of clinical characteristics such as tumor size, location, and stage at diagnosis, as well as treatment approaches including surgery types and their impact on patient outcomes. Additionally, the study will assess the causes of death and overall survival rates among these young patients, aiming to identify any significant prognostic factors. By leveraging the robust and extensive data available in the SEER database, this study seeks to uncover critical insights into the management of follicular and \[specific type\] carcinoma in pediatric and adolescent populations. The findings are expected to contribute to the development of more tailored and effective therapeutic strategies, ultimately improving long-term survival and quality of life for affected patients.

Conditions

• Pediatric and Adolescent Differentiated Thyroid Carcinoma
• SEER Database Analysis

Interventions

Type	Name	Description
OTHER	Different Pathological Types (FTC vs PTC)	Comprehensive Comparison of Pediatric and Adolescent Follicular Thyroid Carcinoma and Papillary Thyroid Carcinoma Patients

Timeline

• Start date: 2000-01-01
• Primary completion: 2020-12-31
• Completion: 2024-08-31
• First posted: 2024-09-19
• Last updated: 2024-09-19