NCT06591247

Membrane Stripping for Cervical Ripening

Evaluation of Stripping for Cervical Ripening - A Randomized Controlled Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 400 (estimated)
• Sponsor: Meir Medical Center · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The goal of this interventional study is to evaluate the effectiveness of membrane stripping in cervical ripening compared to double balloon catheter induction. The study population consists of women undergoing labor induction. The main questions it aims to answer are: 1. Is membrane stripping as effective as double balloon catheter induction in cervical ripening? 2. What is the influence of membrane stripping on the time required for cervical ripening, delivery duration, and maternal and fetal outcomes compared to balloon induction.

Conditions

• Labor, Induced
• Cervical Ripening
• Balloon Induction
• Membrane Stripping
• Pregnancy Related
• Induction of Birth

Interventions

Type	Name	Description
DEVICE	Double Baloon Catheter	A double Baloon Catheter will be inserted for 12 hours to one of the arms of the study
PROCEDURE	Membrane Stripping	Stripping will be considered as 3-5 rotations of separating the amniotic sac from the cervix and will be perfomed twice (every 4-6 hours)
DRUG	PGE2	A PGE2 vaginal pessary (Cervidil) will be inserted for 12-24 hours

Timeline

• Start date: 2024-08-07
• Primary completion: 2027-12-31
• Completion: 2027-12-31
• First posted: 2024-09-19
• Last updated: 2026-04-15

Locations

1 site across 1 country: Israel