NCT06590272

Comparison on Outcomes of Four IOLs in Patients With Cataracts

Comparison on Visual and Refractive Outcomes of Four Different Types of IOL in Patients With Cataracts

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 103 (actual)
• Sponsor: Shanghai 10th People's Hospital · Academic / Other
• Sex: All
• Age: 50 Years – 95 Years
• Healthy volunteers: Not accepted

Summary

The objective of this study was to compare the objective visual outcomes and subjective fuctional vision of four different intraocular lens (IOL) in patients underwent cataracts surgery. This was a retrospective study. Patients with age-related cataract underwent phacoemulsification combined with IOLs implantation. Patients were divided into 4 groups. Uncorrected distant visual acuity(UDVA), uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA),and the best corrected visual acuity (BCVA) 1 month and 3 months after the surgery were determined. The defocus curve, contrast sensitivity, and customized VF-14-oriented Visual Function Index questionnaire were performed 3 months postoperatively. Kruskal-Wallis test and generalized estimating equation(GEE) were used to analyze and compare the difference between objective visual outcomes and subjective visual quality among different groups.

Detailed description

The objective of this study was to compare the objective visual outcomes and subjective fuctional vision of four different intraocular lens (IOL) in patients underwent cataracts surgery. This was a retrospective study. Patients with age-related cataract underwent phacoemulsification combined with IOLs implantation. Patients were divided into group A (TECNIS PCB00 IOL), Group B (HumanOptics Diff-Aay IOL), Group C (TECNIS Symfony ZXR00 IOL) and group D (ZEISS AT LISA tri 839MP IOL). Uncorrected distant visual acuity(UDVA), uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA),and the best corrected visual acuity (BCVA) 1 month and 3 months after the surgery were determined. The defocus curve, contrast sensitivity, and customized VF-14-oriented Visual Function Index questionnaire were performed 3 months postoperatively. Kruskal-Wallis test and generalized estimating equation(GEE) were used to analyze and compare the difference between objective visual outcomes and subjective visual quality among different groups.

Conditions

• Cataract
• Intraocular Lens
• Visual Outcomes

Interventions

Type	Name	Description
DEVICE	TECNIS PCB00 intraocular lens	In this study, we select TECNIS PCB00 IOL for inserting in the eyes during the cataract surgery
DEVICE	HumanOptics Diff-Aay intraocular lens	In this study, we select HumanOptics Diff-Aay IOL for inserting in the eyes during the cataract surgery
DEVICE	TECNIS Symfony ZXR00 intraocular len	In this study, we select TECNIS Symfony ZXR00 IOL for inserting in the eyes during the cataract surgery
DEVICE	ZEISS AT LISA tri 839MP intraocular len	In this study, we select ZEISS AT LISA tri 839MP IOL for inserting in the eyes during the cataract surgery

Timeline

• Start date: 2021-10-01
• Primary completion: 2023-06-30
• Completion: 2023-06-30
• First posted: 2024-09-19
• Last updated: 2024-09-19

Locations

1 site across 1 country: China