NCT06587958

Fermented Plant-based Portfolio Diet 4 Metabolic Health

Fermented Plant-based Portfolio Diet 4 Metabolic Health (FermDiHealth)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 89 (actual)
• Sponsor: Chalmers University of Technology · Academic / Other
• Sex: All
• Age: 20 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The primary objective of this study is to evaluate the metabolic effects of a high-fiber portfolio diet based on fermented plant-based foods compared to a corresponding non-fermented plant-based diet and a control diet (habitual diet). This will be assessed across gut microbiome profiles (high/low Prevotella), focusing on cardiometabolic risk factors, particularly inflammation. A total of 100 men and women who meet all inclusion criteria and none of the exclusion criteria will be invited to participate. The study will employ a three-way randomized, controlled cross-over design, featuring six-week interventions separated by six-week washout periods. Participants will attend the clinic on 15 occasions, including screening visits.

Conditions

• Metabolic Cardiovascular Syndrome

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Fermented plant-based foods	Participants will daily consume five different types of fermented plant-based foods, in addition to their habitual diet.
DIETARY_SUPPLEMENT	Non-fermented plant-based foods	Participants will daily consume five different types of non-fermented plant-based foods, in addition to their habitual diet.
OTHER	Habitual diet	Participants will follow their habitual diet.

Timeline

• Start date: 2024-10-28
• Primary completion: 2025-12-18
• Completion: 2025-12-19
• First posted: 2024-09-19
• Last updated: 2026-03-19

Locations

1 site across 1 country: Sweden