Trials / Not Yet Recruiting
Not Yet RecruitingNCT06587178
Semi-elemental Versus Polymeric EEN in the Preoperative Optimization for Patients with CD
Semi-elemental Versus Polymeric Exclusive Enteral Nutrition in the Preoperative Optimization for Patients with Crohn's Disease: a Randomized Controlled Trial
- Status
- Not Yet Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 304 (estimated)
- Sponsor
- Wei Zhou · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
Growing evidence has shown that exclusive enteral nutrition (EEN) plays an important role in the preoperative optimization for patients with Crohn's disease (CD). However, the efficacy and safety of different types of enteral feeds including semi-elemental and polymeric enteral nutrition on CD have not been investigated. The aim of this study was to compare the role of semi-elemental and polymeric enteral nutrition on CD.
Detailed description
Growing evidence has shown that exclusive enteral nutrition (EEN) plays an important role in the preoperative optimization for patients with Crohn's disease (CD). However, the efficacy and safety of different types of enteral feeds including semi-elemental and polymeric enteral nutrition on CD have not been investigated. The aim of this study was to compare the role of semi-elemental and polymeric enteral nutrition on CD. The primary outcome: the reduction rate of CRP/ALB after exclusive enteral nutrition in Crohn's disease. The other outcomes: (1) the changes in Crohn's disease activity index; (2) the tolerance of enteral nutrition; (3) the changes in body mass index; (4) postoperative complications and the incidence of stoma; (5) the rate of surgery; (6) other adverse reactions.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | peptison liquid | CD patients requiring bowel resection and preoperative EEN were randomized to receive peptison liquid for 6 weeks. |
| DIETARY_SUPPLEMENT | Enteral nutritional suspension | CD patients requiring bowel resection and preoperative EEN were randomized to receive enteral nutritional suspension for 6 weeks. |
Timeline
- Start date
- 2024-10-01
- Primary completion
- 2025-12-30
- Completion
- 2025-12-30
- First posted
- 2024-09-19
- Last updated
- 2024-09-19
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06587178. Inclusion in this directory is not an endorsement.