NCT06584461

Interest of Lidocaine in Children with Upper Airway Infection Undergoing General Anesthesia

Lidocaine in Children with Upper Airway Infection Undergoing General Anesthesia: Interventional Controlled Randomized Double Blind Study

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 102 (actual)
• Sponsor: Tunis University · Academic / Other
• Sex: All
• Age: 12 Months – 14 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to determine whether intravenous (IV) lidocaine reduces the incidence of perioperative respiratory complications (PRCs) in children with upper respiratory tract infections undergoing general anesthesia. The study will also evaluate the safety of IV lidocaine in this population. The main questions it aims to answer are: 1. Does IV lidocaine lower the incidence of perioperative respiratory complications (e.g., laryngospasm, cough, desaturation) compared to a placebo? 2. What are the side effects associated with the administration of IV lidocaine in these children? Researchers will compare IV lidocaine to a placebo to assess its effectiveness in reducing PRCs.

Conditions

• Upper Respiratory Tract Infections
• Perioperative Respiratory Complications

Interventions

Type	Name	Description
DRUG	Lidocaine (drug)	IV lidocaine, administered once during the induction of anesthesia.
DRUG	Saline (NaCl 0,9 %) (placebo)	IV placebo (normal saline), administered once during the induction of anesthesia.

Timeline

• Start date: 2023-01-02
• Primary completion: 2023-12-31
• Completion: 2024-02-05
• First posted: 2024-09-04
• Last updated: 2024-09-19

Locations

1 site across 1 country: Tunisia