NCT06581458

Home Transcranial Direct-Current Stimulation for Motoric Cognitive Risk Syndrome

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 64 (estimated)
• Sponsor: Tel-Aviv Sourasky Medical Center · Other Government
• Sex: All
• Age: 65 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

1. To examine the effect of a two-week tDCS intervention of 3 months of continued tDCS intervention versus 3 months of receiving a placebo treatment (dummy). On the costs of performing an action task (dual task cost) walking speed, cognitive measures and motor function. 2. To examine whether the effects of tDCS build up over time by creating a delayed start mechanism in the intervention (delayed-start design) 3. Examining mechanical and neuroplastic effects of tDCS intervention 4. To examine the response to tDCS over time

Detailed description

* The study aims to investigate the mechanical and neuroplastic effects of a tDCS intervention. * The intervention consists of an initial two-week period of tDCS application, followed by three months of continued tDCS treatment. * A placebo group will receive a dummy treatment for three months to compare the outcomes. * The study will measure various parameters including the costs of performing an action task (dual task cost), walking speed, cognitive measures, and motor function. * A delayed-start design will be used to determine if the effects of tDCS build up over time.

Conditions

• Motoric Cognitive Risk Syndrome

Interventions

Type	Name	Description
DRUG	tDCS	The immediate intervention group will continue to receive five tDCS treatments per week for 6 months. The late intervention group will receive five sham treatments per week for 3 months and then begin receiving five weekly tDCS treatments for an additional 3 months.

Timeline

• Start date: 2024-09-01
• Primary completion: 2026-09-01
• Completion: 2026-09-01
• First posted: 2024-09-03
• Last updated: 2024-09-03