NCT06581211

Aromatherapy Oil Associated for Managing Anxiety and Pain During Bone Marrow Biopsy Procedures

Aromatherapy Oil Associated Changes on Anxiety and Pain During Bone Marrow Biopsy Procedures

• Status: Suspended
• Phase: N/A
• Study type: Interventional
• Enrollment: 45 (estimated)
• Sponsor: City of Hope Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This clinical trial evaluates whether using aromatherapy can reduce pain and anxiety for cancer patients during routine biopsy procedures. Because of the discomfort associated with a bone marrow aspirate and biopsy (BMAB), many patients have significant anxiety in addition to their pain. With the current background of the opioid crisis, researchers have been looking for different ways to treat pain and anxiety in cancer patients without using medications that have a risk for abuse. Recent research suggests that using lavender aromatherapy may be an effective and more affordable treatment for anxiety and pain in patients. Information gathered from this study may help researchers determine whether using aromatherapy may help to manage pain and anxiety during biopsy procedures for cancer patients.

Detailed description

PRIMARY OBJECTIVES: I. To determine the feasibility of utilizing aromatherapy oils during bone marrow biopsy procedures in clinical practice. II. To assess satisfaction of patients receiving aromatherapy oils during bone marrow biopsy procedures in clinical practice. SECONDARY OBJECTIVES: I. To observe the relationship of aromatherapy oils (as compared to placebo aromatherapy) on anxiety in patients undergoing a bone marrow aspirate and biopsy procedure. II. To observe the relationship of aromatherapy oils (as compared to placebo aromatherapy) on pain in patients undergoing a bone marrow aspirate and biopsy procedure. III. To observe the relationship of aromatherapy oils (versus placebo aromatherapy) on other symptoms (i.e., physical, emotional symptoms, etc.). IV. Additionally assess if there are any differences in practitioner procedure evaluation between the groups. OUTLINE: Patients are randomized to 1 of 3 groups. GROUP I: Patients inhale lavender oil aromatherapy (LAO) for 20 minutes prior to standard of care (SOC) BMAB and throughout the procedure. GROUP II: Patients inhale linalool oil aromatherapy (LA) for 20 minutes prior to SOC BMAB and throughout the procedure. GROUP III: Patients inhale jojoba oil aromatherapy for 20 minutes prior to SOC BMAB.

Conditions

• Hematopoietic and Lymphatic System Neoplasm
• Malignant Solid Neoplasm

Interventions

Type	Name	Description
PROCEDURE	Aromatherapy and Essential Oils	Inhale LA
OTHER	Electronic Health Record Review	Ancillary studies
OTHER	Jojoba Oil	Inhale jojoba oil aromatherapy
OTHER	Lavender Oil	Inhale LAO
OTHER	Questionnaire Administration	Ancillary studies

Timeline

• Start date: 2024-08-23
• Primary completion: 2026-06-25
• Completion: 2026-06-25
• First posted: 2024-09-03
• Last updated: 2025-11-06

Locations

2 sites across 1 country: United States