NCT06579521

Real-world Experiences of Alcohol and Cognitions Over Time

Connecting Alcohol Myopia to Real-World Risk Behaviors Through Cognitive Ecological Momentary Assessment (REACT Phase II: Lab and EMA)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 92 (actual)
• Sponsor: University of Washington · Academic / Other
• Sex: All
• Age: 21 Years – 25 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to examine how alcohol affects young adults' attention in both laboratory and real-world settings through phone-based cognitive tasks. The main questions this trial is designed to answer are: * How well do the phone-based cognitive tasks capture alcohol's effects on attention? * Does the effect of alcohol on attention contribute to risk-taking? Participants will complete cognitive tasks to assess attention before and after consuming a standard amount of alcohol in the laboratory, and during surveys completed through a phone app for eight weekends.

Detailed description

The goal of this study is to develop cognitive tasks that assess alcohol-related attentional narrowing (i.e., alcohol myopia) for smartphone-based ecological momentary assessment (EMA). In Phase I, tasks were adapted from computer to smartphone format and refined through interviews with young adults who provided feedback on mock-ups. In Phase II (the current trial), feasibility, acceptability, reliability, and validity of the adapted tasks will be tested in lab and EMA. Young adults who pass an online pre-screening and phone screening will complete an initial lab session involving self-report questionnaires, alcohol consumption (target breath alcohol concentration \[BrAC\] = .08%), and general cognitive and myopia-specific tasks. All participants in Phase II will be assigned to receive a dose of alcohol in the lab session; task performance will be compared within individuals from before to after they are intoxicated. Participants will remain in the lab until their BrAC reduces to a level of .03% and they can pass a field sobriety test. These same participants will then complete EMA while wearing transdermal alcohol biosensors for 8 consecutive weekends, including one morning survey and at least two evening surveys per day. Then, participants will return to the lab for a follow-up session involving self-report questions and an interview eliciting additional feedback. Findings will help to clarify the role of alcohol myopia as a mechanism linking intoxication to real-world risk behaviors.

Conditions

• Alcohol Intoxication

Interventions

Type	Name	Description
OTHER	Alcohol	A standard dose of alcohol will be administered (volume calculated with regard to age, sex assigned at birth, height, and weight) in the form of vodka and combined with mixer at a 1:4 ratio to reach a target breath alcohol concentration of .08%.

Timeline

• Start date: 2024-08-18
• Primary completion: 2025-08-31
• Completion: 2025-08-31
• First posted: 2024-08-30
• Last updated: 2025-12-17

Locations

1 site across 1 country: United States