NCT06576648

Thailand HIV and Stigma Reduction Study

Optimizing Mobile Interventions to Overcome Stigma and Promote HIV Prevention

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 154 (estimated)
• Sponsor: University of Massachusetts, Worcester · Academic / Other
• Sex: Male
• Age: 18 Years – 29 Years
• Healthy volunteers: Accepted

Summary

This project will develop a multi-component, technology-delivered intervention designed to reduce HIV and intersectional stigma and improve the use of HIV pre-exposure prophylaxis (PrEP) among HIV-negative Thai vulnerable emerging adults (18-29 years).

Conditions

• Pre-Exposure Prophylaxis

Interventions

Type	Name	Description
BEHAVIORAL	Mobile Healthy Choices (mHC)	mHC is a four-session, 20-minute, motivational interviewing-based intervention, which will be delivered on the CIAS platform. It will be tailored to participants' responses given during the interaction in the intervention. In the first two sessions, the (virtual) counselor will motivate participants to overcome stigma and utilize HIV prevention services by using tailored motivational interviewing strategies, develop an individualized change goal based on their readiness, and provide cognitive behavioral strategies. In the last two sessions, the counselor will review the change plan, monitor progress, and provide support for sustained behavioral change. The sessions will occur within three months after baseline.
BEHAVIORAL	Finding Respect and Ending Stigma around HIV (FRESH)	FRESH content includes six 10-15 minute sessions with interactive, culturally sensitive multimedia modules, which will be delivered on the CIAS platform. The content will aim to improve self-efficacy, reduce intersectional stigmas and promote HIV preventative behaviors. The sessions will occur within three months after baseline.
BEHAVIORAL	Standard PrEP Counseling	All participants will receive one-on-one, face to face counseling from focusing on sexual and behavioral risk assessment for HIV/STIs, risk reduction, and HIV prevention. For those not on PrEP, the sessions will focus on risk perception, awareness of PrEP, and facilitators and barriers to PrEP access. For those on PrEP, the sessions will focus on adherence. The counseling will be provided at baseline, 3 months, and 6 months.

Timeline

• Start date: 2025-02-20
• Primary completion: 2026-12-31
• Completion: 2027-08-14
• First posted: 2024-08-29
• Last updated: 2025-09-08

Locations

3 sites across 1 country: Thailand