NCT06576154

The Role of Antibiotic Prophylaxis in Lowering Wound Infection Rates Post-Open Repair of Primary Elective Groin Hernias in High-Risk Patients

The Role of Antibiotic Prophylaxis in Lowering Wound Infection Rates Post-Open Repair of Primary Elective Groin Hernias in High-Risk Patients: A Randomized Control Trial.

• Status: Recruiting
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: University of Aleppo · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study aims to investigate the impact of antibiotic prophylaxis on reducing wound infection rates following open repair of primary elective groin hernias in high-risk patients.

Detailed description

This study will be a randomized controlled trial involving high-risk patients undergoing open repair of primary elective groin hernias. Participants will be randomized into two groups: one receiving antibiotic prophylaxis and the other serving as the control group. The study will assess the incidence of wound infections postoperatively in both groups to determine the effectiveness of antibiotic prophylaxis in lowering infection rates.

Conditions

• Antibiotic Prophylaxis
• Wound Infection
• Groin Hernia

Interventions

Type	Name	Description
DRUG	Cefazolin 1000 MG	* Medication: Cefazolin * Dosage: 1 gram * Administration Timing: A single dose will be administered preoperatively.

Timeline

• Start date: 2024-08-01
• Primary completion: 2025-08-01
• Completion: 2025-09-01
• First posted: 2024-08-28
• Last updated: 2024-08-28

Locations

1 site across 1 country: Syria