Trials / Recruiting
RecruitingNCT06575738
Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents
Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide - in Adolescents (the PRESSURE Trial)
- Status
- Recruiting
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- Sponsor
- University of Colorado, Denver · Academic / Other
- Sex
- All
- Age
- 12 Years – 24 Years
- Healthy volunteers
- Not accepted
Summary
The study plans to learn more about what happens to the body after bariatric surgery in people 12 to 24 years old. The study aims to understand why people respond differently to bariatric surgery and how to define success beyond weight loss alone. The study also plans to learn more about whether a medication (semaglutide) can help people 12 to 24 years old who, between 1 and 2 years after bariatric surgery, have not lost as much weight as expected.
Conditions
- Obesity
- Adolescent Obesity
- Body-Weight Trajectory
- Weight Loss Trajectory
- Bariatric Surgery
- Anti-obesity Agents
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Injectable semaglutide | Subcutaneous weekly injectable semaglutide |
| BEHAVIORAL | Standard postoperative care | Standard postoperative care consists of behaviorally-focused interventions delivered by the interdisciplinary Bariatric Surgery Center team targeting nutrition, physical activity, sleep, and mental health at standard postoperative intervals. |
Timeline
- Start date
- 2024-10-11
- Primary completion
- 2027-09-01
- Completion
- 2027-10-01
- First posted
- 2024-08-28
- Last updated
- 2026-01-12
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT06575738. Inclusion in this directory is not an endorsement.