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CompletedNCT06575595

Pharmacokinetic (PK) Characterization of Subcutaneous Tulisokibart (MK-7240-010)

A Pharmacokinetic Study of Tulisokibart Administered Subcutaneously Via Autoinjector or Syringe in Healthy Adult Participants

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
60 (actual)
Sponsor
Merck Sharp & Dohme LLC · Industry
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

The primary objectives of the study are to characterize the pharmacokinetics (PK) of a single subcutaneous (SC) dose of tulisokibart (MK-7240) administered via autoinjector (AI) (Treatment A) and to characterize the PK of different concentrations of tulisokibart following SC administration of a single dose via vial/syringe (Treatments B and C). There is no formal hypothesis.

Conditions

Interventions

TypeNameDescription
BIOLOGICALTulisokibartsingle dose via SC autoinjector (Treatment A) or concentration A or concentration B SC injection via syringe and vial (Treatments B and C)

Timeline

Start date
2024-09-24
Primary completion
2025-01-31
Completion
2025-01-31
First posted
2024-08-28
Last updated
2025-02-18

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT06575595. Inclusion in this directory is not an endorsement.

Pharmacokinetic (PK) Characterization of Subcutaneous Tulisokibart (MK-7240-010) (NCT06575595) · Clinical Trials Directory