NCT06573632

Perioperative TPN Improves Surgical Outcomes

Does Perioperative Parenteral Nutrition Affect Outcome in Patients Undergoing Major Abdominal Surgeries

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 150 (actual)
• Sponsor: Nepal Medical College and Teaching Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Preoperative optimization of patients is a well known concept. Not all patients can tolerate feeds and as such TPN is given. TPN given preoperatively and continued postoperatively in selected group of patients can significantly improve the surgical outcomes and lower the morbidity as well as mortality. So the investigators aim to find the impact of TPN in malnutritional surgical patients.

Detailed description

Any patient who is at risk of malnutrition as well as already malnutritioned were given preoperative TPN for 5 days. After 5 days, elective surgery was done and TPN was continued postoperatively until patient could consume 50% of their daily requirements orally. Patients who underwent emergency surgeries were also enrolled in this study as these patients could receive TPN only postoperatively. Daily patient charting with Clavien Dindo Classification, length of stay and mortality were mentioned and verified by the operating surgical team. Data was maintained electronically by the surgical team. Data was also entered in MS-EXCEL at the time of patient discharge. Since data was maintained on everyday basis till patient discharge and does not include follow-ups, there are no missing data. Upon completion of study, all data will be exported to SPSS and analyzed accordingly using means, SDs, Chi-square and Fisher exact test.

Conditions

• Parenteral Nutrition
• Major Surgery
• Malnutrition

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	TPN-N7 Baxter	providing TPN to all malnutrition patients preoperatively as well as postoperatively.

Timeline

• Start date: 2022-10-01
• Primary completion: 2023-01-01
• Completion: 2023-01-01
• First posted: 2024-08-27
• Last updated: 2024-08-27

Locations

1 site across 1 country: Nepal