NCT06573333

Effects of Timing of Cord Clamping on Serum Calcium Levels in Neonates

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: College of Physicians and Surgeons Pakistan · Academic / Other
• Sex: All
• Age: 1 Minute – 6 Hours
• Healthy volunteers: Accepted

Summary

Title: Effect of timing of cord clamping of serum calcium levels in neonates Background: Hypocalcemia is a common metabolic problem in neonatal period. Most cases of hypocalcemia are asymptomatic however, the symptomatic cases require prompt management. Objective: The objective is to determine the effects of early and delayed cord on serum calcium level in neonates Study Design: Randomized Controlled Trial

Detailed description

Place and Duration of Study: PEMH Rawalpindi and CMH Rawalpindi from January 2024 to July 2024. Patients and Methods: Total sample size of 200 neonates will be included in the study divided into four groups with cord clamping at 15s, 30s, 60s, 120s each group will have a total of 50 neonates. Blood sampling for CBC / CRP / S. Electrolytes (Na, K, Total Ca, Ionized Ca, Mg), S Calcitonin, ABGs (HCO3 Levels) samples will be collected at 6 hours of life. * Inclusion Criteria: Neonates born at gestational age 37 weeks to 41 weeks with no maternal complication. Parents who give consent for inclusion in the study * Exclusion Criteria: Mothers with evidence of clinical disease (diabetes, preeclampsia, hypertension). Babies with congenital malformations and intrauterine growth restriction. Expected Results: Research data on serum Calcium levels in neonates have shown no correlation to timing of cord clamping. Same results are expected in this study.

Conditions

• Serum Calcium Concentration

Interventions

Type	Name	Description
PROCEDURE	Umblical Cord Clamping	Umbilical Cord will be clamped using a plastic clamp at the noted time after delivery of the neonate

Timeline

• Start date: 2024-01-01
• Primary completion: 2024-09-30
• Completion: 2024-09-30
• First posted: 2024-08-27
• Last updated: 2024-08-27

Locations

1 site across 1 country: Pakistan