NCT06571383

STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight Loss

Weight Maintenance in Adolescents With Obesity; Long-Term Treatment With Semaglutide s.c.2.4 mg Once-weekly

• Status: Active Not Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 500 (estimated)
• Sponsor: Novo Nordisk A/S · Industry
• Sex: All
• Age: 12 Years – 15 Years
• Healthy volunteers: Not accepted

Summary

The study is testing how well semaglutide can help adolescents with excess body weight to lose weight and to maintain weight loss. All participants in the study will receive semaglutide as a weekly injection. The study medicine is injected with a thin needle in the stomach, thighs or upper arms. All participants will get semaglutide treatment for a minimum of 3 years.

Conditions

• Obesity

Interventions

Type	Name	Description
DRUG	Semaglutide	Participants will receive semaglutide s.c(under the skin) once weekly.

Timeline

• Start date: 2024-09-17
• Primary completion: 2028-11-15
• Completion: 2031-11-15
• First posted: 2024-08-26
• Last updated: 2025-12-18

Locations

93 sites across 13 countries: United States, Belgium, Canada, Denmark, France, Germany, Greece, Italy, Mexico, Poland, Saudi Arabia, Sweden, United Kingdom

Regulatory

• FDA-regulated drug study