NCT06570967

A Clinical Study of Hyperthyroidism in Children

A Retrospective and Prospective Observational Study of Hyperthyroidism in Children

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Shengjing Hospital · Academic / Other
• Sex: All
• Age: 29 Days – 14 Years
• Healthy volunteers: Not accepted

Summary

This study intends to conduct a retrospective and prospective study on children with hyperthyroidism, and it is a non-intervention study to collect information on diagnosis and treatment and long-term follow-up of children with hyperthyroidism. To investigate the clinical characteristics, treatment effect, side effects and remission of hyperthyroidism in children, to analyze the predictive factors for the effect of antithyroid drug treatment, remission and recurrence after drug withdrawal, and to explore the risk factors related to the occurrence of antithyroid drug-related adverse reactions.

Conditions

• Hyperthyroidism

Interventions

Type	Name	Description
DRUG	Methimazole(MMI)	The initial dose of methimazole was 0.2-0.8 mg/(kg▪d). This dose was subsequently reduced by 25% to 50% and adjusted to maintain euthyroidism, based on the results of serum thyroid hormone testing during follow-up.

Timeline

• Start date: 2023-07-18
• Primary completion: 2026-12-01
• Completion: 2027-12-01
• First posted: 2024-08-26
• Last updated: 2024-08-27

Locations

1 site across 1 country: China