Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06568562

XL092 in Patients With Metastatic Castration-Resistant Prostate Cancer

PRO-XL: A Phase II Study of XL092 in Patients With Metastatic Castration-Resistant Prostate Cancer After Progression on Lutetium-177 (177Lu)-PSMA-617

Status
Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
32 (estimated)
Sponsor
University of Utah · Academic / Other
Sex
Male
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine how well the study drug XL092 is helping to treat a participant's cancer after 16 weeks of treatment. Researchers will also look at how safe the XL092 is and how well the XL092 is working. XL092 is an oral tablet that will be taken once a day. Participants will return to clinic for regular visits for checkups and tests.

Conditions

Interventions

TypeNameDescription
DRUGXL092XL092 will be supplied as a tablet that will be taken at home once a day. Participants should drink at least 8 ounces of water with each dose of XL092. Participants should not eat at least 2 hours before taking the dose and 1 hour after. Participants will be given enough XL092 to take at home for a full cycle.

Timeline

Start date
2024-12-09
Primary completion
2026-12-01
Completion
2028-12-01
First posted
2024-08-23
Last updated
2025-12-09

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT06568562. Inclusion in this directory is not an endorsement.