NCT06568055

A Study of Cytomegalovirus (CMV) Infection After Kidney Transplant in Adults in the United Kingdom

Investigation of Refractory CMV (Cytomegalovirus) Infection or Disease, After Kidney Transplantation, Using UK (United Kingdom) National Registry of Rare Kidney Diseases (RaDaR)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 330 (actual)
• Sponsor: Takeda · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This observational study intends to retrospectively gather information on cytomegalovirus (CMV) infection management in the United Kingdom (UK) over a period of 7 years (2017-2024). The main aims of this study are the following: * To estimate the overall prevalence and annual rate of adults with refractory CMV infection after a kidney transplant and describe how such CMV infections are treated * To describe how effective and well-tolerated the treatment was. * To describe the demographic and clinical characteristics of adult participants with CMV infection (refractory and non-refractory). In this study, already existing data will be reviewed and analysed from a UK database called the Registry of Rare Kidney Diseases (RaDaR) (NCT06065852). The study will only review data collected as part of routine clinical practice. The study will not impact the standard medical care and treatment of participants.

Conditions

• Cytomegalovirus (CMV)

Interventions

Type	Name	Description
OTHER	No Intervention	This is non-interventional study.

Timeline

• Start date: 2024-09-30
• Primary completion: 2025-10-31
• Completion: 2025-12-31
• First posted: 2024-08-23
• Last updated: 2026-01-29

Locations

1 site across 1 country: United Kingdom