NCT06566664

Peripheral Neurostimulation for Nerve Block Placement

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 82 (estimated)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Peripheral nerve blocks are routinely used and highly successful for intra-operative anesthesia and post-operative pain management. Nerve blocks are guided using either neurostimulation as a means to localize the right nerve or by ultrasound guidance or combining the 2 methods. The purpose of this study is to assess whether electrical stimulation improves nerve block quality, beyond its simple purpose of nerve localization.

Detailed description

The investigators wish to understand how electrical stimulation can affect local anesthetic disposition when performing a peripheral nerve block. By studying this subject, the investigators open possibilities for improvement on many levels: increasing the efficacy of the nerve block allows for a reduced onset time, reduced incidence of incomplete block and prolonged duration of the local anesthetics. This allows for patients to fully benefit from the analgesic properties of the nerve block, allows for a decrease in delays for the operating room readiness, and a decrease in the amount of medication needed for a successful nerve block. This will decrease side effects and risks of the nerve blocks. Overall better post-surgical pain control may decrease risks for developing chronic post-operative pain, a major post-operative complication. The results of this study will open the door to novel approaches to manage acute post-operative pain.

Conditions

• Pain Syndrome
• Pain Management

Interventions

Type	Name	Description
DEVICE	B Braun HNS 12 nerve stimulator	Nerve stimulator that is traditionally used for nerve localization during block placements.
DEVICE	B Braun HNS 12 nerve stimulator sham control	Stimulator will be placed and turned on, but the grounding electrode will not be connected to prevent nerve stimulation.

Timeline

• Start date: 2025-07-23
• Primary completion: 2026-07-30
• Completion: 2026-07-30
• First posted: 2024-08-22
• Last updated: 2026-01-26

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study