Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06566508

Effectiveness of Asiaticoside as Intracanal Medication on Infectious/Inflammatory Contents in Teeth With Apical Periodontitis

Status
Recruiting
Phase
Phase 2 / Phase 3
Study type
Interventional
Enrollment
36 (estimated)
Sponsor
Mansoura University · Academic / Other
Sex
All
Age
20 Years – 60 Years
Healthy volunteers
Accepted

Summary

The objective of this study is to investigate \"clinically\" the effectiveness of Asiaticoside based intracanal medication compared to the commonly used intracanal medicaments (calcium hydroxide Ca(OH)2 and Ledermix) on the levels of bacteria and inflammatory cytokines in root canals and periradicular tissues of teeth with apical periodontitis.

Detailed description

This study investigate \"clinically\" the effectiveness of Asiaticoside based intracanal medication compared to the commonly used intracanal medicaments (calcium hydroxide Ca(OH)2 and Ledermix) on the levels of bacteria and inflammatory cytokines in root canals and periradicular tissues of teeth with apical periodontitis.

Conditions

Interventions

TypeNameDescription
DRUGCalcium Hydroxide Intracanal medicationCalcium Hydroxide Intracanal medication
DRUGLeddermix Intracanal medicationLeddermix Intracanal medication
DRUGAsiaticoside Intracanal medicationAsiaticoside Intracanal medication

Timeline

Start date
2023-11-20
Primary completion
2024-06-05
Completion
2025-03-03
First posted
2024-08-22
Last updated
2024-08-22

Locations

1 site across 1 country: Egypt

Source: ClinicalTrials.gov record NCT06566508. Inclusion in this directory is not an endorsement.