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Trials / Enrolling By Invitation

Enrolling By InvitationNCT06565572

Antisense Oligonucleotide Treatment for PCARP Disease Due to Mutation in FLVCR1

An Open-label Single Center, Single Participant Study of an Experimental Antisense Oligonucleotide Treatment for PCARP (Posterior Column Ataxia with Retinitis Pigmentosa) Disease Due to Mutations in FLVCR1

Status
Enrolling By Invitation
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
1 (estimated)
Sponsor
University of Colorado, Denver · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

The goal of this clinical trial is to evaluate a specific antisense oligonucleotide medication in one patient with posterior column ataxia with retinitis pigmentosa. The main question it aims to answer is: what is the safety and tolerability of this medication in a single participant.

Conditions

Interventions

TypeNameDescription
DRUGnL-FLVC-001nL-FLVC-001 is an antisense oligonucleotide that will be injected into the vitreous

Timeline

Start date
2023-08-23
Primary completion
2024-08-21
Completion
2028-12-31
First posted
2024-08-22
Last updated
2025-01-27

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT06565572. Inclusion in this directory is not an endorsement.