NCT06561672

Paracetamol Plus Tramadol Versus Fentanyl As Preemptive Analgesia For Enhanced Recovery After Day Case Surgeries

Paracetamol Plus Tramadol Versus Fentanyl As Preemptive Analgesia For Enhanced Recovery

• Status: Enrolling By Invitation
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 102 (estimated)
• Sponsor: Zagazig University · Other Government
• Sex: All
• Age: 21 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Implementation of enhanced recovery in day case surgeries using either preemptive intravenous paracetamol plus tramadol or preemptive intravenous fentanyl.

Detailed description

after being informed about the study and potential risks. All patients giving written consent will be randomized by double blind manner into two equal groups (T group and F group). Using computer generated randomization table; each group consists of 51 patients:Group (T) (n=51): Patients will receive preemptive intravenous infusion of tramadol plus paracetamol . Group (F) (n=51): Patients will receive preemptive intravenous fentanyl.

Conditions

• Preemptive Paracetamol Plus Tramadol and Preemptive Fentanyl

Interventions

Type	Name	Description
DRUG	tramadol plus paracetamol	Intravenous infusion of 15mg/kg paracetamol together with 1mg/kg tramadol will be started and to be finished before starting of induction of anesthesia (induction agent will be propofol 2mg/kg and muscle relaxant (cisatracurium) 0.15 mg/kg)
DRUG	Fentanyl	Intravenous injection of 1.5 microgram/kg fentanyl will be given to the patient followed by induction agents (propofol 2mg/kg).
DRUG	propofol and muscle relaxant (cisatracurium)	propofol 2mg/kg and muscle relaxant (cisatracurium) 0.15 mg/kg)
DRUG	Propofol	propofol 2mg/kg

Timeline

• Start date: 2024-09-01
• Primary completion: 2025-03-20
• Completion: 2025-06-20
• First posted: 2024-08-20
• Last updated: 2024-08-20

Locations

1 site across 1 country: Egypt