NCT06561165

Multifocal HD-tDCS and Motor Function

Personalizing Multifocal Transcranial Direct Stimulation Dose to Target the Motor Network in Older Adults

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: University of Michigan · Academic / Other
• Sex: All
• Age: 65 Years – 85 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to understand how the brain controls movement and how Non-invasive Brain Stimulation (NIBS) with a technique called High-density transcranial direct current stimulation (HD-tDCS) can alter brain processes to improve behavior. Participants in this study will be randomized to either HD-tDCS with standard intervention or personalized dose-controlled multifocal network-targeted HD-tDCS. The hypothesis is that dexterous hand function will improve after a standard HD-tDCS dose and increase even more after personalized dose-controlled multifocal network-targeted HD-tDCS.

Detailed description

This project is the first of two projects. The second project will be registered as a separate project in the future and enroll participants from this project.

Conditions

• Healthy

Interventions

Type	Name	Description
DEVICE	Standard HD-tDCS intervention	Participants will have three sessions along with behavioral assessments.
DEVICE	Multifocal network targeted HD-tDCS intervention	Participants will have three sessions along with behavioral assessments.
DEVICE	Functional Magnetic Resonance Imaging (fMRI)	Participants will have an MRI before or after having HD-tDCS intervention.

Timeline

• Start date: 2025-02-25
• Primary completion: 2027-01-25
• Completion: 2027-01-25
• First posted: 2024-08-19
• Last updated: 2026-02-17

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study