Trials / Recruiting
RecruitingNCT06557057
Impact of Aromatase Inhibitor Therapy on Glucose Homeostasis and Diabetes Risk
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 66 (estimated)
- Sponsor
- Mayo Clinic · Academic / Other
- Sex
- Female
- Age
- —
- Healthy volunteers
- Accepted
Summary
This study assesses the effect of hormone directed treatment for breast cancer on glucose metabolism.
Detailed description
PRIMARY OBJECTIVE: I. Assess the impact of endocrine adjuvant therapy with aromatase inhibitors in women with hormone receptor positive breast cancer, ductal carcinoma in situ (cancer, DCIS ), or women with other high risk breast conditions, on various indices of glucose homeostasis, utilizing oral minimal model assessment, in comparison to healthy post menopausal women and another cohort of women on tamoxifen. OUTLINE: This is an observational study. Patients undergo blood sample collection, glucose testing, dual-energy x-ray absorptiometry (DEXA) scan to measure body composition, complete a questionnaire and have their medical records reviewed on study.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Non-Interventional Study | Non-Interventional Study |
Timeline
- Start date
- 2023-11-16
- Primary completion
- 2026-12-01
- Completion
- 2026-12-01
- First posted
- 2024-08-16
- Last updated
- 2026-03-31
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT06557057. Inclusion in this directory is not an endorsement.