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Trials / Not Yet Recruiting

Not Yet RecruitingNCT06556186

Surgical and Pharmacological Efficacy of Knosp Grade 0-2 Prolactinoma

Status
Not Yet Recruiting
Phase
N/A
Study type
Interventional
Enrollment
600 (estimated)
Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University · Academic / Other
Sex
All
Age
20 Years – 40 Years
Healthy volunteers
Not accepted

Summary

The investigators carried out a multi-center comparative study, involving hospitals including the Second Affiliated Hospital of Zhejiang University School of Medicine, Peking Union Medical College Hospital, West China Hospital, Wenzhou First Hospital, and Li Huili Hospital. This study aimed to compare the efficacy of medication and surgery for specific subtypes of microadenomas and clearly defined macroadenomas (Knosp grades 0-2), in order to determine which is more effective and which has fewer benefits, thereby enhancing the evidence base.

Conditions

Interventions

TypeNameDescription
PROCEDURETransnasal transsphenoidal pituitary lesion resection under neuroendoscopyTransnasal transsphenoidal pituitary lesion resection under neuroendoscopy
DRUGBromocriptin 2.5mg, 2-3 times a dayBromocriptin 2.5mg, 2-3 times a day

Timeline

Start date
2024-10-01
Primary completion
2027-03-31
Completion
2027-03-31
First posted
2024-08-15
Last updated
2024-08-15

Source: ClinicalTrials.gov record NCT06556186. Inclusion in this directory is not an endorsement.