NCT06554665

Powering Up Stroke Rehabilitation Through HIIT

Powering Up Stroke Rehabilitation Through High-Intensity Interval Training

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 66 (estimated)
• Sponsor: The Hong Kong Polytechnic University · Academic / Other
• Sex: All
• Age: 50 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Objectives: To investigate the effects of high-intensity interval training (HIIT) on musculoskeletal fitness in chronic stroke survivors. Hypothesis to be tested: HIIT, performed on a recumbent stepper, will significantly enhance muscle power in chronic stroke survivors when compared with moderate-intensity continuous training (MICT) Design and subjects: Assessor-blinded, stratified, randomised, placebo-controlled clinical trial involving eligible 66 chronic stroke survivors. Interventions: Participants will be randomly allocated to one of three groups: the HIIT group, the MICT group, or a stretching group (active control). Each group will attend sessions three times per week for 12 consecutive weeks, totaling 36 training sessions. Main outcome measures: Assessments will be conducted at baseline, at mid-term of the intervention (week 6), at the end of the intervention (week 12), and at a 12-week follow-up (week 24). The primary outcome measure will be muscle power. Secondary outcome measures will include muscle strength, body composition, biomarkers, motor function, balance function, cardiorespiratory response, and psychosocial response.

Conditions

• Stroke

Interventions

Type	Name	Description
BEHAVIORAL	High-intensity Interval Training	There will be three sessions per week for 12 consecutive weeks, totaling 36 training sessions.
BEHAVIORAL	Moderate-Intensity Continuous Training	There will be three sessions per week for 12 consecutive weeks, totaling 36 training sessions.
BEHAVIORAL	Stretching	There will be three sessions per week for 12 consecutive weeks, totaling 36 training sessions.

Timeline

• Start date: 2024-08-20
• Primary completion: 2026-04-06
• Completion: 2026-04-30
• First posted: 2024-08-15
• Last updated: 2026-03-27

Locations

1 site across 1 country: Hong Kong