NCT06551701

ACHIEVE Pilot Statins for Vascular Protection

A Cluster-randomized Trial to Improve Use of High IntEnsity Statins for Vascular Protection

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 225 (actual)
• Sponsor: Duke University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

ACHIEVE aims to increase statin usage among patients with ASCVD by having a pharmacist talk to patients and providers.

Detailed description

Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death in the United States (U.S.) Statins reduce the risk of cardiovascular events by 30% in those with prior history of ASCVD. Despite being inexpensive and well-tolerated, however, statins are underused in clinical practice, particularly in patients who identify as Black. A large-scale intervention to improve evidence-based statin initiation among individuals with ASCVD is needed, particularly for the Black population. To meet this need, we aim to conduct a multi-center, pragmatic, cluster randomized, controlled trial to assess the impact of a provider- and patient-directed intervention to increase the prescription of, and adherence to, appropriate statin therapy among those with ASCVD (ACHIEVE: A Controlled trial to improve use of High IntEnsity statins for Vascular protEction). The intervention will be pharmacist-led, embedded in commercial payer systems, partnering with the National Committee for Quality Assurance (NCQA), and with a particular emphasis on improving statin use in the Black population.

Conditions

• ASCVD

Interventions

Type	Name	Description
OTHER	Pharmacist call	Pharmacists will call patients and their providers to discuss benefits of statin use

Timeline

• Start date: 2025-05-19
• Primary completion: 2025-07-31
• Completion: 2026-02-28
• First posted: 2024-08-13
• Last updated: 2025-08-07

Locations

2 sites across 1 country: United States